Formulation and in vitro evaluation of inosine acedoben dimepranol tablets

نویسندگان

چکیده

The present work was carried out to formulate and evaluate immediate release tablets of Inosine Acedoben Dimepranol (IAD). Tablets were prepared by wet granulation process overcome the poor compression properties IAD powder produce high-dose tablets. Various type binders disintegrants like Povidone K-30, K-25, wheat starch, mannitol used prepare some series Granules evaluated for pre-compression parameters post- parameters. composition batch № L03 best producing 500 mg optimal lubricant is glycerol dibehenate at a concentration 3.08%. Optimized formulation in-vitro dissolution test. Stability studies performed selected composition.

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ژورنال

عنوان ژورنال: ????????

سال: 2022

ISSN: ['2411-6076', '2709-135X']

DOI: https://doi.org/10.3897/pharmacia.69.e81442